Hazard statement · Health hazards
What does H350 mean?
May cause cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard> .
- Hazard class
- Carcinogenicity, Hazard Category 1A, 1B (Carc. 1A / Carc. 1B)
- Pictogram
GHS08Health hazard- Signal word
- Danger
Categories and label elements
| CLP abbreviation | Pictogram | Signal word |
|---|---|---|
| Carc. 1A | GHS08Health hazard | Danger |
| Carc. 1B | GHS08Health hazard | Danger |
Related precautionary statements (P codes)
The precautionary statements that CLP Annex IV assigns to this class. Not all of them go on the label: under CLP Article 28(3), no more than six precautionary statements appear on the label unless the nature and severity of the hazard require more; the selection depends on the product and its users.
Build a label with this class. The free label tool works out the pictogram, the signal word and the P statements for the label from the classes you choose.
When does a mixture need H350?
For a pure substance H350 comes straight from the classification; for a mixture it is derived from component data. The calculation rules applied to this code are:
- Carc. 1A: Threshold method: a Carc. 1A component at ≥ 0.1 % gives the mixture the same class. (CLP Annex I Table 3.6.2)
- Carc. 1A: If a component has a harmonised specific concentration limit (SCL) and meets it, the mixture takes the corresponding class directly.
- Carc. 1B: Threshold method: a Carc. 1B component at ≥ 0.1 % gives the mixture the same class. (CLP Annex I Table 3.6.2)
For a step-by-step worked example see classifying a mixture under CLP.
Where is H350 written in the SDS?
In the prepared SDS the class "Carc. 1A / Carc. 1B" is matched with the code in Section 2.1, the text of H350 is written in Section 2.2 next to the pictogram and signal word, and the class of the component shows up in Section 3. Section 16 collects the full text of the H statements cited by code. For H350, it appears in Section 11 (toxicological information), under heading 11.1, as a "Classified" line when the class is among the classes of the mixture.
How does H350 appear on the label?
When you see H350 on a label it is accompanied by GHS08 (health hazard), and it is written with the signal word "Danger". In the Chemoris template Section 2.2 carries at most 8 H statements; if the limit is exceeded the least severe ones are dropped and a warning is shown. For the bottom of the label, 6 P statements are candidates for this class in CLP Annex IV; under CLP Article 28 at most 6 of them are selected.
Where does it appear in the safety data sheet?
- Section 2.1: classification; the class abbreviation and H350 are given together.
- Section 2.2: label elements; H350 with its full text, pictogram and signal word.
- Section 3: composition table; in the row of every component that has this class.
- Section 16: the full text of the H statements cited as codes in earlier sections.
Class criteria and thresholds for H350
The values below come from the Chemoris rule file (CLP Annex I). They show the condition under which H350 arises in a mixture. For physical hazards and other classes that depend on test data, the result comes from the mixture's own measurement, not from component percentages.
| Class | Criterion | Limit / formula | Source |
|---|---|---|---|
| Carc. 1A | Single-component concentration limit | Carc. 1A component ≥ 0.1 % | CLP Annex I Table 3.6.2 |
| Carc. 1B | Single-component concentration limit | Carc. 1B component ≥ 0.1 % | CLP Annex I Table 3.6.2 |
H350 compared with H350i and H351
The table below puts H350 next to its closest neighbouring statements; the values are read from the rule data.
| Hazard statement | H350 | H350i | H351 |
|---|---|---|---|
| Class abbreviation | Carc. 1A / Carc. 1B | Carc. 1A / Carc. 1B | Carc. 2 |
| Pictogram | GHS08 | GHS08 | GHS08 |
| Signal word | Danger | Danger | Warning |
| Precautionary statements assigned | 6 | 6 | 6 |
| Concentration cut-off in a mixture | — | — | — |
H350 and H350i carry the same signal word (Danger). Both are shown with the same pictogram (GHS08). The signal word differs: Danger for H350, Warning for H351. Both are shown with the same pictogram (GHS08).
In which SDS sections does H350 appear?
H350 does not stay only in the label section of an SDS; the class itself and the precautionary statements assigned to it shape the content of other sections too. The counts are calculated from the P statements that Annex IV assigns to this class.
| SDS section | Relation to this code |
|---|---|
| 2.1 Classification | Written with the abbreviation Carc. 1A / Carc. 1B and the code H350. |
| 2.2 Label elements | H350 appears with its full text, GHS08 (health hazard) and “Danger”. |
| 3 Composition | The class and code show in the row of every component that carries this class. |
| 11 Toxicological information | The health effect is justified here under the relevant endpoint heading. |
| 4 First aid | Of the 6 assigned P statements, 1 belong to the subject of this section: P308+P313. |
| 7 Handling and storage | Of the 6 assigned P statements, 3 belong to the subject of this section: P201, P202, P405. |
| 8 Exposure controls / PPE | Of the 6 assigned P statements, 1 belong to the subject of this section: P280. |
| 13 Disposal | Of the 6 assigned P statements, 1 belong to the subject of this section: P501. |
| 16 Other information | The full text of the H statements cited by code is collected here. |
Statements that appear on the label together with H350
H350 is never printed alone on a label; it sits next to the pictogram and the signal word. The Chemoris selection method (response, prevention, storage, disposal in that order; core statements first) gives these first 5 candidates for this class:
(Carc. 1A)
| Rank | P code | Type | Priority | Text |
|---|---|---|---|---|
| 1 | P308+P313 | response | core | IF exposed or concerned: Get medical advice/attention. |
| 2 | P201 | prevention | core | Obtain special instructions before use. |
| 3 | P202 | prevention | core | Do not handle until all safety precautions have been read and understood. |
| 4 | P280 | prevention | core | Wear protective gloves/protective clothing/eye protection/face protection. |
| 5 | P405 | storage | core | Store locked up. |
The GHS08 pictogram and “Danger” are printed together. This ranking applies because a label usually carries at most 6 statements; when a combined statement is selected, its parts are not printed again.
Official EU wording of H350 in other languages
When a product is exported to the EU, the SDS and label are expected in the official language of the Member State where it is placed on the market (REACH Article 31(5)). The table gives the official wording of H350 from the CLP Annex III/IV language versions published in the Official Journal of the European Union. Source: EUR-Lex CELEX 02008R1272-20260701.
| Language | Official wording | Class title | Signal word |
|---|---|---|---|
| German | Kann Krebs erzeugen < Expositionsweg angeben, sofern schlüssig belegt ist, dass diese Gefahr bei keinem anderen Expositionsweg besteht> . | Karzinogenität, Gefahrenkategorie 1A, 1B | Gefahr |
| French | Peut provoquer le cancer <indiquer la voie d'exposition s'il est formellement prouvé qu'aucune autre voie d'exposition ne conduit au même danger> . | Cancérogénicité, catégories de danger 1A, 1B | Danger |
| Spanish | Puede provocar cáncer <indíquese la vía de exposición si se ha demostrado concluyentemente que el peligro no se produce por ninguna otra vía> . | Carcinogenicidad, categorías 1A y 1B | Peligro |
| Italian | Può provocare il cancro <indicare la via di esposizione se è accertato che nessun'altra via di esposizione comporta il medesimo pericolo> . | Cancerogenicità, categorie di pericolo 1A e 1B | Pericolo |
| Polish | Może powodować raka <podać drogę narażenia, jeżeli definitywnie udowodniono, że inna droga narażenia nie powoduje zagrożenia> . | Rakotwórczość, kategoria zagrożeń 1A, 1B | Niebezpieczeństwo |
| Dutch | Kan kanker veroorzaken < blootstellingsroute vermelden indien afdoende bewezen is dat het gevaar bij andere blootstellingsroutes niet aanwezig is > | Kankerverwekkendheid, gevarencategorie 1A en 1B | Gevaar |
| Portuguese | Pode provocar cancro < indicar a via de exposição se existirem provas concludentes de que o perigo não decorre de nenhuma outra via de exposição >. | Carcinogenicidade, categorias de perigo 1A, 1B | Perigo |
| Romanian | Poate provoca cancer <indicați calea de expunere, dacă există probe concludente că nicio altă cale de expunere nu provoacă acest pericol> . | Cancerigenitate, categoriile de pericol 1A, 1B | Pericol |
Common mistakes with H350
- Writing unlimited H statements for a multi-class product: in the Chemoris template, Section 2.2 holds at most 8 H statements.
Next steps
To read a statement like H350 correctly on a label and in an SDS, see the guide How to read H and P codes; to pick the class and prepare the label automatically, use the free label tool.
Related hazard statements
Other H statements in the same hazard family as H350 (Carc.). The difference between categories mostly comes from the degree of severity.
Frequently asked questions
Which pictogram and signal word go with H350 on a label?
For H350 the pictogram is GHS08 (health hazard); it is written with the signal word "Danger".
How many P statements does H350 need?
CLP Annex IV assigns 6 precautionary statements to the class of H350, but under CLP Article 28(3) a label usually carries at most 6 of them; the selection depends on the product and its user.
When does a mixture need H350?
Threshold method: a Carc. 1A component at ≥ 0.1 % gives the mixture the same class. If a component has a harmonised specific concentration limit (SCL) and meets it, the mixture takes the corresponding class directly. Details are in the section "When does a mixture need H350?" above.
In which SDS sections does H350 appear?
H350 appears in Sections 2.1 (classification), 2.2 (label), 3 (composition) and 16, and also in 11, 4, 7, 8 and 13.
What is the difference between H350 and H350i?
H350 carries Danger and GHS08; H350i carries Danger and GHS08.
Which numerical limits apply to H350 in a mixture?
Carc. 1A: Carc. 1A component ≥ 0.1 %; Carc. 1B: Carc. 1B component ≥ 0.1 %.
Source: Regulation (EC) No 1272/2008 (CLP) Annexes I and III; Turkish SEA Regulation (Official Gazette 28848). The statement is the official English text of CLP Annex III. Pictogram and signal word: CLP Annex I Table 3.6.3. Updated: 6 November 2026.
Prepare your SDS