Hazard statement · Health hazards

What does H350i mean?

May cause cancer by inhalation.

Hazard class
— (Carc. 1A / Carc. 1B)
Pictogram
GHS08Health hazard
Signal word
Danger

Categories and label elements

CLP abbreviationPictogramSignal word
Carc. 1AGHS08Health hazardDanger
Carc. 1BGHS08Health hazardDanger

Related precautionary statements (P codes)

The precautionary statements that CLP Annex IV assigns to this class. Not all of them go on the label: under CLP Article 28(3), no more than six precautionary statements appear on the label unless the nature and severity of the hazard require more; the selection depends on the product and its users.

Prevention

  • P201Obtain special instructions before use.
  • P202Do not handle until all safety precautions have been read and understood.
  • P280Wear protective gloves/protective clothing/eye protection/face protection.

Response

  • P308+P313IF exposed or concerned: Get medical advice/attention.

Storage

  • P405Store locked up.

Disposal

  • P501Dispose of contents/container to …

Build a label with this class. The free label tool works out the pictogram, the signal word and the P statements for the label from the classes you choose.

When does a mixture need H350i?

For a pure substance H350i comes straight from the classification; for a mixture it is derived from component data. The calculation rules applied to this code are:

  • Carc. 1A: Threshold method: a Carc. 1A component at ≥ 0.1 % gives the mixture the same class. (CLP Annex I Table 3.6.2)
  • Carc. 1A: If a component has a harmonised specific concentration limit (SCL) and meets it, the mixture takes the corresponding class directly.
  • Carc. 1B: Threshold method: a Carc. 1B component at ≥ 0.1 % gives the mixture the same class. (CLP Annex I Table 3.6.2)

For a step-by-step worked example see classifying a mixture under CLP.

Where is H350i written in the SDS?

In the prepared SDS the class "Carc. 1A / Carc. 1B" is matched with the code in Section 2.1, the text of H350i is written in Section 2.2 next to the pictogram and signal word, and the class of the component shows up in Section 3. Section 16 collects the full text of the H statements cited by code. For H350i, it appears in Section 11 (toxicological information), under heading 11.1, as a "Classified" line when the class is among the classes of the mixture.

How does H350i appear on the label?

When you see H350i on a label it is accompanied by GHS08 (health hazard), and it is written with the signal word "Danger". In the Chemoris template Section 2.2 carries at most 8 H statements; if the limit is exceeded the least severe ones are dropped and a warning is shown. For the bottom of the label, 6 P statements are candidates for this class in CLP Annex IV; under CLP Article 28 at most 6 of them are selected.

Where does it appear in the safety data sheet?

  • Section 2.1: classification; the class abbreviation and H350i are given together.
  • Section 2.2: label elements; H350i with its full text, pictogram and signal word.
  • Section 3: composition table; in the row of every component that has this class.
  • Section 16: the full text of the H statements cited as codes in earlier sections.

Class criteria and thresholds for H350i

The values below come from the Chemoris rule file (CLP Annex I). They show the condition under which H350i arises in a mixture. For physical hazards and other classes that depend on test data, the result comes from the mixture's own measurement, not from component percentages.

ClassCriterionLimit / formulaSource
Carc. 1ASingle-component concentration limitCarc. 1A component ≥ 0.1 %CLP Annex I Table 3.6.2
Carc. 1BSingle-component concentration limitCarc. 1B component ≥ 0.1 %CLP Annex I Table 3.6.2

H350i compared with H350 and H351

The table below puts H350i next to its closest neighbouring statements; the values are read from the rule data.

Hazard statementH350iH350H351
Class abbreviationCarc. 1A / Carc. 1BCarc. 1A / Carc. 1BCarc. 2
PictogramGHS08GHS08GHS08
Signal wordDangerDangerWarning
Precautionary statements assigned666
Concentration cut-off in a mixture———

H350i and H350 carry the same signal word (Danger). Both are shown with the same pictogram (GHS08). The signal word differs: Danger for H350i, Warning for H351. Both are shown with the same pictogram (GHS08).

H350 H351

In which SDS sections does H350i appear?

H350i does not stay only in the label section of an SDS; the class itself and the precautionary statements assigned to it shape the content of other sections too. The counts are calculated from the P statements that Annex IV assigns to this class.

SDS sectionRelation to this code
2.1 ClassificationWritten with the abbreviation Carc. 1A / Carc. 1B and the code H350i.
2.2 Label elementsH350i appears with its full text, GHS08 (health hazard) and “Danger”.
3 CompositionThe class and code show in the row of every component that carries this class.
11 Toxicological informationThe health effect is justified here under the relevant endpoint heading.
4 First aidOf the 6 assigned P statements, 1 belong to the subject of this section: P308+P313.
7 Handling and storageOf the 6 assigned P statements, 3 belong to the subject of this section: P201, P202, P405.
8 Exposure controls / PPEOf the 6 assigned P statements, 1 belong to the subject of this section: P280.
13 DisposalOf the 6 assigned P statements, 1 belong to the subject of this section: P501.
16 Other informationThe full text of the H statements cited by code is collected here.

Statements that appear on the label together with H350i

H350i is never printed alone on a label; it sits next to the pictogram and the signal word. The Chemoris selection method (response, prevention, storage, disposal in that order; core statements first) gives these first 5 candidates for this class:

(Carc. 1A)

RankP codeTypePriorityText
1P308+P313responsecoreIF exposed or concerned: Get medical advice/attention.
2P201preventioncoreObtain special instructions before use.
3P202preventioncoreDo not handle until all safety precautions have been read and understood.
4P280preventioncoreWear protective gloves/protective clothing/eye protection/face protection.
5P405storagecoreStore locked up.

The GHS08 pictogram and “Danger” are printed together. This ranking applies because a label usually carries at most 6 statements; when a combined statement is selected, its parts are not printed again.

Official EU wording of H350i in other languages

When a product is exported to the EU, the SDS and label are expected in the official language of the Member State where it is placed on the market (REACH Article 31(5)). The table gives the official wording of H350i from the CLP Annex III/IV language versions published in the Official Journal of the European Union. Source: EUR-Lex CELEX 02008R1272-20260701.

LanguageOfficial wordingClass titleSignal word
GermanKann bei Einatmen Krebs erzeugen.—Gefahr
FrenchPeut provoquer le cancer par inhalation.—Danger
SpanishPuede provocar cáncer por inhalación.—Peligro
ItalianPuò provocare il cancro se inalato.—Pericolo
PolishWdychanie może spowodować raka.—Niebezpieczeństwo
DutchKan kanker veroorzaken bij inademing.—Gevaar
PortuguesePode causar cancro por inalação.—Perigo
RomanianPoate provoca cancer prin inhalare.—Pericol

Common mistakes with H350i

  • Writing unlimited H statements for a multi-class product: in the Chemoris template, Section 2.2 holds at most 8 H statements.

Next steps

To read a statement like H350i correctly on a label and in an SDS, see the guide How to read H and P codes; to pick the class and prepare the label automatically, use the free label tool.

Other H statements in the same hazard family as H350i (Carc.). The difference between categories mostly comes from the degree of severity.

  • H350May cause cancer <state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard> .
  • H351Suspected of causing cancer < state route of exposure if it is conclusively proven that no other routes of exposure cause the hazard >.

Frequently asked questions

Which pictogram and signal word go with H350i on a label?

For H350i the pictogram is GHS08 (health hazard); it is written with the signal word "Danger".

How many P statements does H350i need?

CLP Annex IV assigns 6 precautionary statements to the class of H350i, but under CLP Article 28(3) a label usually carries at most 6 of them; the selection depends on the product and its user.

When does a mixture need H350i?

Threshold method: a Carc. 1A component at ≥ 0.1 % gives the mixture the same class. If a component has a harmonised specific concentration limit (SCL) and meets it, the mixture takes the corresponding class directly. Details are in the section "When does a mixture need H350i?" above.

In which SDS sections does H350i appear?

H350i appears in Sections 2.1 (classification), 2.2 (label), 3 (composition) and 16, and also in 11, 4, 7, 8 and 13.

What is the difference between H350i and H350?

H350i carries Danger and GHS08; H350 carries Danger and GHS08.

Which numerical limits apply to H350i in a mixture?

Carc. 1A: Carc. 1A component ≥ 0.1 %; Carc. 1B: Carc. 1B component ≥ 0.1 %.

Source: Regulation (EC) No 1272/2008 (CLP) Annexes I and III; Turkish SEA Regulation (Official Gazette 28848). The statement is the official English text of CLP Annex III. Pictogram and signal word: CLP Annex I Table 3.6.3. Updated: 6 November 2026.