What does H310 mean?

Categories and label elements

CLP abbreviation	Pictogram	Signal word
Acute Tox. 1	GHS06Skull and crossbones	Danger
Acute Tox. 2	GHS06Skull and crossbones	Danger

Related precautionary statements (P codes)

The precautionary statements that CLP Annex IV assigns to this class. Not all of them go on the label: under CLP Article 28(3), no more than six precautionary statements appear on the label unless the nature and severity of the hazard require more; the selection depends on the product and its users.

When does a mixture need H310?

Whether a mixture needs H310 is calculated from the classes and concentrations of its components. The values in the rule file for this code are:

• A component of this class is taken into account in a mixture only at a concentration of ≥ 0.1 %. (CLP Annex I Table 1.1)
• The category of the mixture is calculated from the ATE values of the components (route: dermal) with the additivity formula 100/ATEmix = Σ(Ci/ATEi).

For a step-by-step worked example see classifying a mixture under CLP.

Where is H310 written in the SDS?

H310 is tracked in three places of the SDS: the classification line in Section 2.1 ("Acute Tox. 1 / Acute Tox. 2"), the label elements in Section 2.2 and the component list in Section 3. Section 16 repeats the explanation of the code. In addition, it is justified in Section 11 (toxicological information) under the relevant effect heading.

How does H310 appear on the label?

The label elements for H310 are: pictogram GHS06 (skull and crossbones); it is written with the signal word "Danger". In the Chemoris template Section 2.2 carries at most 8 H statements; if the limit is exceeded the least severe ones are dropped and a warning is shown. For the bottom of the label, 10 P statements are candidates for this class in CLP Annex IV; under CLP Article 28 at most 6 of them are selected.

Where does it appear in the safety data sheet?

• Section 2.1: classification; the class abbreviation and H310 are given together.
• Section 2.2: label elements; H310 with its full text, pictogram and signal word.
• Section 3: composition table; in the row of every component that has this class.
• Section 16: the full text of the H statements cited as codes in earlier sections.

Class criteria and thresholds for H310

The values below come from the Chemoris rule file (CLP Annex I). They show the condition under which H310 arises in a mixture. For physical hazards and other classes that depend on test data, the result comes from the mixture's own measurement, not from component percentages.

H310 compared with H311 and H312

The table below puts H310 next to its closest neighbouring statements; the values are read from the rule data.

H310 and H311 carry the same signal word (Danger). Both are shown with the same pictogram (GHS06). The signal word differs: Danger for H310, Warning for H312. The pictogram differs: GHS06 for H310, GHS07 for H312.

H311 H312

In which SDS sections does H310 appear?

H310 does not stay only in the label section of an SDS; the class itself and the precautionary statements assigned to it shape the content of other sections too. The counts are calculated from the P statements that Annex IV assigns to this class.

Statements that appear on the label together with H310

H310 is never printed alone on a label; it sits next to the pictogram and the signal word. The Chemoris selection method (response, prevention, storage, disposal in that order; core statements first) gives these first 5 candidates for this class:

(Acute Tox. 1)

The GHS06 pictogram and “Danger” are printed together. This ranking applies because a label usually carries at most 6 statements; when a combined statement is selected, its parts are not printed again.

Official EU wording of H310 in other languages

When a product is exported to the EU, the SDS and label are expected in the official language of the Member State where it is placed on the market (REACH Article 31(5)). The table gives the official wording of H310 from the CLP Annex III/IV language versions published in the Official Journal of the European Union. Source: EUR-Lex CELEX 02008R1272-20260701.

Common mistakes with H310

• Mixing up exposure routes: H310 concerns only the dermal route; ATE is calculated separately for each route (CLP Annex I 3.1.3.6.1 (formula), Table 3.1.1 (category ranges), Table 3.1.2 (converted ATE)).
• Pouring every P candidate onto the label: there are 10 candidates, but CLP Article 28(3) limits a label to 6 precautionary statements (up to 8 when needed).
• Writing unlimited H statements for a multi-class product: in the Chemoris template, Section 2.2 holds at most 8 H statements.

Next steps

To read a statement like H310 correctly on a label and in an SDS, see the guide How to read H and P codes; to pick the class and prepare the label automatically, use the free label tool.

Related hazard statements

Other H statements in the same hazard family as H310 (Acute Tox.). The difference between categories mostly comes from the degree of severity.

• H300Fatal if swallowed.
• H301Toxic if swallowed.
• H302Harmful if swallowed.
• H311Toxic in contact with skin.
• H312Harmful in contact with skin.
• H330Fatal if inhaled.
• H331Toxic if inhaled.
• H332Harmful if inhaled.

Frequently asked questions